Pharmacyclics is a biopharmaceutical company focused on developing and commercializing small-molecule drugs for the treatment of cancer and immune mediated diseases. Co. has three proprietary drug candidates under clinical development and several preclinical lead molecules: an inhibitor of Bruton's tyrosine kinase (BTK) ibrutinib in several Phase III studies in hematologic malignancies, a BTK inhibitor lead optimization program targeting anti-inflammatory and autoimmune indications, an inhibitor of Factor VIIa in a Phase II clinical trial in pancreatic cancer and a histone deacetylase inhibitor, abexinostat, in Phase I and II clinical trials in solid tumors and hematological malignancies.
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